Tuesday, July 29, 2014

The Benefits of GP Winstrol

GP Winstrol is a very popular testosterone derived anabolic steroid from the Dihydrotestosterone (DHT) family that is available as an oral tablet or as an injectable in the form of Winstrol Depot. First developed by Sterling-Winthrop Laboratories in the early 1960’s the active hormone in the compound Stanozolol was given the trade name “Winstrol” and as is common in the anabolic steroid world the first trade name ever given has been the name most associate with the steroid. While many anabolic steroids are normally only found in certain circles some are found across the board in every athletic category imaginable GP Winstrol is such a steroid.  Winstrol is an ester free DHT steroid found in the form of a 17-Alpha-Alkylated steroid (17-aa) form as well as an injectable aqueous suspension (suspended in water.) Pertaining to the oral form the 17-aa alteration simply refers to the altered chemical structure that occurs at the 17th carbon position; without such restructuring the steroid would be useless in oral form. The 17-aa alteration allows the steroid to survive the first pass through the liver after ingestion and absorb into the blood stream where it becomes active, this has both positive and negative effects. The good news is once ingested it will enter the blood very rapidly, the bad news is it will bring about a level of toxicity to the liver as is common with most oral medications, steroidal and non-steroidal alike. 

As it pertains to the injectable aqueous form the same active Stanozolol hormone is being used, in that there is no difference. However, the toxicity to the liver will not be as large of a concern with the injectable form as by injecting the medication it goes to work directly and bypasses the first pass through the liver completely. Another important distinction is in the half-life, injectable GP Winstrol carries with it a half-life of approximately 24 hours while the oral Winny form as it is commonly known carries with it a half-life of approximately 9 hours. As you can see that’s a pretty big difference and administration will necessarily vary from one form to the next if absolute efficiency is going to be met.

As a DHT based steroid GP Winstrol is extraordinarily anabolic and only slightly androgenic, regardless of the form you choose this will hold true as will all other traits. As a powerful anabolic steroid GP Winstrol greatly enhances protein synthesis via its ability to dramatically increase nitrogen retention in the muscles all the while possessing no aromatase effects. Most all steroids can provide quality benefits to most any cycle for any purpose, however, most anabolic androgenic steroids generally have one primary purpose and secondary characteristics that may be apt for another cycle. For example, the powerful steroid Anadrol is used primarily as a bulking steroid as its nature is best suited for this purpose, however, it does possess traits that can be beneficial in a cutting cycle when used properly, this is very common in competitive bodybuilding circles. GP Winstrol however is a little different, while its primary purpose is without question a cutting cycle and in the aid in athletic performance there is not much use for this steroid in a bulking cycle as it is not by its mode of action designed to build large amounts of lean tissue. Even so, regarding cutting and athletic performance GP Winstrol is often a fine choice.

The primary benefit revolving around Winstrol are without question increases in strength and this can relate to physical power, speed and agility; further, as by its nature Winstrol can greatly enhance vascularity as well as promote a dryer and harder physique when body-fat is already low. While GP Winstrol will not specifically burn stored body-fat, most steroids won’t, it will have a very positive effect on this process. Winny is an excellent steroid for preservation purposes when in a caloric deficit as you should be if you are dieting and the more lean tissue we can hold onto when in this deficit the greater your metabolic rate will be, thereby leading to a leaner and harder physique.  Like all anabolic steroids Winstrol is not without the possibility of negative side-effects, however, the effects are often highly overstated and can largely be controlled by responsible use. Individual sensitivity will also play a role and the extent can vary from one person to the next as this is the case with all medications, steroidal and non-steroidal alike.

As discussed, liver toxicity is a concern, especially with the oral form as the oral form is a 17-aa steroid. Due to this fact we will necessarily limit the total time of Winstrol to 6-8 weeks at a time in order to protect the liver. However, while use will increase liver enzymes, in most all cases your liver will return to normal levels once use is discontinued and will never experience toxic levels anywhere near what daily alcohol consumption can bring and even regular use of many over the counter medications.

Friday, July 25, 2014

Benefits of Ipamorelin peptide

Like the GHRP-6 peptide (growth hormone releasing hexapeptide), it is a synthetic peptide that has powerful Growth Hormone releasing properties. And these GH releasing properties are what is of interest to athletes and bodybuilders since they can make a tremendous difference in the amount of muscle you can grow and how quickly you burn fat.

Whereas GHRP-6 is a hexapeptide, Ipamorelin is a penta-peptide.The strength it displays may very well make regular old Growth Hormone (GH) obsolete. But what athletes and bodybuilders really want to know is what is this wonder peptide capable of doing, how is it used, and how does it compare to the other GHRP peptides? Athletes are taking Ipamorelin in a 200mcg -300mcg dosage, two or three times daily, using a tiny insulin needle to inject. They usually start with the lower dose since side effects can include headaches or what feels like a head-rush. Ipamorelin can be taken at anytime but taking it about 30-45 minutes before a workout would seem ideal because of the pulse in Growth Hormone (GH) it creates allowing for maximum growth.

Studies on the effects of Ipamorelin on bone growth, body weight, and GH release showed some interesting conclusions.

In one experiment, various doses were administered over the course of 15 days to test the group's reactions.

There was a distinct and dose-dependent effect on body weight gain however, the treatment group did not show a change in total IGF-I levels. Nor did the treatment group produce serum markers of bone development. For example, the number of cells in the wide portion of the tibia (the shinbone) did not change significantly. This is a good thing because it suggests muscle growth with less potential for deformity of bone or cartilage.

The reaction of the pituitary to an aggressive i.v. dose of Ipamorelin showed that plasma GH levels were notably reduced whereas they were unchanged after a comparable dose of GHRH. This is actually a good thing as it suggests that Ipamorelin may not decrease your body's natural GH production - further demonstrating that Ipamorelin is a selective GH releaser.

GHRP-6Unlike GHRP-6, Ipamorelin does not induce hunger making it advantageous to those on a restricted calorie diet. And obviously, Ipamorelin's side-effects are enhanced when combined with anabolic steroids since they too influence Growth Hormone/Insulin Growth Factor release and production. In another study in rats, Ipamorelin released GH from rat pituitary cells as effectively as GHRP-6. Another document states that in healthy swine, Ipamorelin released GH with a consistency that is very comparable to GHRP-6. Also noteworthy was that none of the GH releasers tested affected FSH, LH, PRL or TSH blood serum plasma levels.

Ipamorelin in theory may increase Acetylchloine or Cortisol when used in higher dosages. However, and increase in Acetylchloine or Cortisol is even more likely with GHRP-2 and GHRP-6. In fact, in the case of Ipamorelin, there was little to no rise in Acetylcholine and Cortisol blood plasma levels even at injections more than 200 times higher than the effective dosage for comparable GH release.

This clearly proves that Ipamorelin is the first successful GHRP receptor agonist or chemical that binds to a receptor of a cell and triggers a response by that cell with a specific selectivity for the promotion of GH release by itself. Another advantage to Ipamorelin is that it doesn't cause sudden spikes in prolactin or cortisol as does GHRP-2 and GHRP-6. Ipamorelin is slower in its delivery unlike GHRP's which spike GH levels at a more rapid rate. The slower release is more natural and has a more sustained effect.

All in all it looks as if Ipamorelin is the new wave in GH releasing peptides. It appear to be more potent, longer lasting and potentially safer to use in the long run. More studies are being conducted all the time but as it stands, Ipamorelin looks like a serious contender in the arsenal of anabolic advancement.

Monday, July 14, 2014

Benefits of Femara (Letrozole)

Femara (Letrozole) is a type II (non-steroidal) third generation aromatase inhibitor. Clinically it is used to treat postmenopausal women with either estrogen receptor positive or estrogen receptor unknown breast cancer. In women, tumors that contain estrogen receptors are classified as estrogen receptor-positive (ER+) tumors. For Letrozole to be prescribed, a given tumor must have been diagnosed as estrogen receptor positive or estrogen receptor unknown. In the world of bodybuilding it is used to reduce or eliminate excess estrogen caused by the use of aromatizing steroids.

Letrozole was originally sold under the brand name Femara, and produced by the pharmaceutical house Novartis. It was patented on July 25th, 1997. Letrozole is known  as a type II aromatase inhibitor, meaning, in simplest terms that it attaches to the aromatase enzyme and prevents it from converting androgens to estrogen. In slightly more complex terms, estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme, and letrozole actually inhibits the production of estrogens in by competitive, (reversible) binding to the heme of the relevant cytochrome P450 unit. Letrozole is currently the most powerful aromatase inhibitor available. In women with breast cancer, it has been shown to reduce estrogen levels by 98% or more. However, it’s use and benefits are not limited to eliminating estrogen in women.

In one male test subject Letrozole was able to reduce estrogen levels to undetectable levels, and in another clinical study done on both young and elderly men, intravenous administration of Letrozole lowered Estrogen by 46% in the young men tested, and 62% in the elderly subjects. Because estrogen is part of the negative feedback loop of the HPTA, Letrozole (and other anti-estrogens) are able to raise testosterone in male subjects. Letrozole was studied in men, and found to significantly increase LH levels to a 339 and 323% in the young and the elderly, respectively and Testosterone by 146 and 99%, respectively. Letrozole was also able to produce a peak LH response to Gonadatropin Releasing Hormone equal to a 152 and 52% increase from baseline in either young or older men, respectively. In a similar study 0.02 mg of Letrozole increased testosterone by 45% after 2 days. That same twenty micrograms of Letrozole was also enough, in one study done on men, to reduce estrogen levels by roughly a third. Letrozole has a 2-4 day half-life, and it needs to be taken for up to 60 days to get a steady blood plasma level. Letrozole was used in a rodent study to effectively destroy (benign) breast tissue tumors, which may potentially indicate its use in males attempting to remove gynecomastia (aka gyno). As estrogen is also a factor in stopping linear bone growth, Letrozole is currently being examined for potential use in delay of growth seen in children.

In the world of bodybuilding where more is often thought to be better, Letrozole stands almost alone as an exception to that rule. Estrogen is necessary for healthy immune function, healthy cholesterol levels, joint health, cognitive function, and even aids in muscle growth. In my own experience as well as the experience of many bodybuilders and athletes I’ve worked with, Letrozole simply causes estrogen to be reduced to levels too low to function properly. Unfortunately, this compromised my immune system and joint integrity. For most recreational steroid users, Letrozole is going to be too harsh, and cause too many problems. Still, people can use it effectively if they don’t use the manufacturer’s clinical dose (2.5mgs) and instead keep their dose to .25-1mg. There are, however, better choices for an anti-estrogen. I should mention that using Letrozole at such a low dose does happen to make it a very good economic choice compared with other aromatase inhibitors.

For pre-contest bodybuilders, Letrozole is almost a necessity to eliminate water retention and achieve the ripped look necessary to compete in today’s bodybuilding world. However, in my experience, it is only necessary to be used for the last 4-6 weeks, to eliminate excess estrogen and water retention. After using Letrozole I recommend staying away from any estrogen suppression for at least a month to try to normalize the body.

Wednesday, July 9, 2014

Deca Durabolin popular cycle for bodybuilders

If you want to use an anabolic steroid that is effective and affordable besides being safe and free from side effects of steroids and performance enhancing drugs, Deca Durabolin, which is also known as Deca and Nandrolone decanoate, will be an ideal choice for you. Deca Durabolin has an active life of 14-16 days and is detectable over a period of 16-18 months. Belonging to the category of anabolic-androgenic steroids and classified as a 2.16 anabolic steroid, Deca is a highly effective drug that is available in different forms such as creams, pills, capsules, and gels. Medically, the drug is advised to stimulate immune system enhancements and offer dramatic relief to HIV/AIDS patients and even treat specific blood disorders as part of the adjuvant therapy. This steroid is used by sportsmen to benefit from the improved recuperation time between workouts, protein synthesis, and nitrogen retention. Moreover, this steroid is admired as its use even for long anabolic steroid cycles does not result in side effects like oily skin, male pattern baldness, and prostate complications. If that was not all, Deca use is considered of great use to mask minor joint pain and old nagging injuries besides reducing the inflammation of soft tissues and promoting masculine (secondary sexual) characteristics, including growth of the vocal cords, testicles, and body hair. This steroid is commonly used in doses of 300-800 mg per week by men and 50-100 mg per week by women or in doses of 600 mg per week for 12-16 weeks by men for bulking cycles and 400 mg per week for 12-16 weeks by men in cutting cycles.

A popular Deca Durabolin cycle is all about using Dianabol-30 mg every day for week 1-3 and then 40 mg every day for week 4-6 and complementing it with Sustanon 250 mg every week for week 1-12, Clomid 50 mg every week for week 10-12, and Deca Durabolin-200 mg for the first week and then 300 mg per week for 2nd and 3rd weeks, and 400 mg every week for 4th and 5th weeks, and 300 mg every week for the sixth week. Overdosing or use of low grade or abuse of Deca Durabolin can lead to side effects such as may even cause heart attack, edema, prostate enlargement, menstrual problems, liver toxicity, liver damage, and gynecomastia (female-like breasts). It may even cause elevated blood pressure, shrinking of the testicles, bone age advancement, bad effect on cholesterol levels, increased aggression, oily skin, acne, clitoral hypertrophy, infertility, and sexual dysfunction and therefore it is best to use it only after a qualified medical practitioner has authorized its use after evaluating all medical reports and history. Deca Durabolin, which is also known as Deca and Nandrolone decanoate, is one of the best performance enhancing drugs and anabolic steroids when it comes to stimulating endurance and muscle function gains.

The steroid is popular among both amateur and professional sportsmen when it comes to improving the levels of recuperation time between workouts, protein synthesis, and nitrogen retention. The fact that the use of Deca is not related to side effects like oily skin, male pattern baldness, and prostate complications means that it can even be used by those who are prone to these side effects. However, it is best to seek medical advice before making such use and buy Deca Durabolin only from a legal and reputed website. Since this steroid has a very low rate of aromatization that is approximately 20 percent the rate of testosterone, it does not result in estrogenic or androgenic side effects and gives ample opportunities for sportsmen and others to stay high on the sense of well being, lean muscle mass, and unmatched body strength and muscle mass. Deca Durabolin is best used in doses of 600 mg per week for 12-16 weeks by men for bulking cycles and 400 mg per week for 12-16 weeks by men in cutting cycles or in doses of 300-800 mg per week for men (or 2 mg per lb of body weight) and 50-100 mg per week for women. This anabolic steroid is commonly stacked by sportsmen with steroids and performance enhancing drugs such as testosterone cypionate, testosterone suspension, testosterone enanthate, testosterone propionate, Anadrol, Dianabol, and Sustanon 250 and should always be used under medical supervision and for legal purposes as Deca Durabolin abuse can lead to side effects atrophy of the breasts, early epiphyseal closure, hypercalcaemia, hypercalciuria, withdrawal of ovarian action, decreased ejaculatory volume, and more-than-average increase in bone development, suppression of ovarian activity, oedema, and depression. Use of this steroid is not recommended to those suffering prostate cancer, breast cancer, testicular cancer, high blood pressure, stroke, liver damage, kidney damage, jaundice, hepatic carcinoma, or renal failure.

Thursday, July 3, 2014

Injectable Steroids Propionat 100 by Dragon Pharma

Propionat 100- testosterone propionate is a male sexual hormone with pronounced, mainly androgenic action, possessing the biological and therapeutic properties of the natural hormone. In a healthy male organism, androgens are formed by the testes and adrenal cortex. It is normally produced in women in small physiological quantities.
In addition to the specific action that determines the sexual characteristics of the individual, it also has a general anabolic action, manifested in enhancement of protein synthesis. Under the effect of testosterone, body weight increases and urea excretion is reduced. High doses suppress the production of hypophyseal gonadotropin, while low doses stimulate it. It has an anti tumor effect on mammary gland metastases.

The effective dose has a range between 300mg to 2000mg per week for men. For women, the dose is 50mg-100mg per week. Propionat 100 from Dragon Pharma, the injectable steroid that represents the substance testosterone propionate. Propionat 100 is being shipped in its original box containing a 10 ml vial of 100mg/ml, thus it is an original Dragon Pharma product properly marked and labeled. There is also a special bulk offer for it, specially designed for professionals and for those who prefer cycling regularly.

Testosterone Propionate was one of the first anabolic androgenic steroids ever synthesized and made ready for human use in mass production and as such is one of the most popular anabolic steroids of all time. While there are hundreds of anabolic steroids and forms within each, Testosterone-Propionate is largely one of the easiest to understand as it is very basic in composition and simply a pure testosterone. However, as simple as it is it further remains very powerful and highly effective yet many understand Testosterone-Propionate as well as they understand the most basic algorithms used in space exploration.

Testosterone-Propionate like all forms of testosterone is highly anabolic and androgenic, equal in both rights. As by its nature it is simply a synthetic version of the testosterone hormone naturally produced in the human body by both men and women and essential to a properly functioning endocrine system. While inadequate levels, particularly low levels are generally not life threatening they can be quite bothersome and can lead to more serious problems when not dealt with appropriately. To give you an idea of the importance of the hormone we only need look at the effects of low levels; those who suffer from low testosterone find a body transformation in the opposite desired direction to be very common place; increased body-fat, decreased muscle tissue and strength can all occur and be very difficult to deal with and in many cases impossible when levels are too low. Further, because testosterone is responsible in part for sexual function many men find they experience a decrease in libido, erectile dysfunction when levels are too low, as well as lack of mental focus, energy and even the onset of depression. While these are not life threatening conditions on their own, as you can easily see some of them are pretty serious and there isn’t one any man would wish to have bestowed on him. Conversely, when we look at the effects of low testosterone we can easily see how increased levels would have the opposite effect; take each condition previously listed and take it in the opposite direction towards improvement, which is exactly why testosterone is known as a performance enhancer.

By its very nature Testosterone Propionate dramatically increases nitrogen retention in the muscle allowing protein to be stored in the muscle to a larger degree; as protein is the building block of muscle and increased lean tissue improves our metabolic rate, on this basis alone we have a highly desirable hormone; however, the good news does not end there. As by its mode of action testosterone has the ability to block and reduce muscle wasting hormones known as glucocortico steroid, most commonly cortisol. While testosterone truly has seemingly limitless properties, as it pertains to performance, of particular interest is its ability to greatly increase IGF 1 production in the body, as you understand IGF 1 is a very powerful peptide hormone of a highly anabolic nature and plays a key role alongside human growth hormone, another potent peptide based hormone.